Subutex Vs. Methadone: 3 Factors To Consider

Subutex and Methadone are both FDA-approved medications for opioid addiction treatment. While both are equally effective, they differ in their active ingredients, formulations, and long-term benefits. 

• Subutex has Buprenorphine as an active ingredient and has a lower risk of dependency and overdose. 
• Subutex has a ceiling effect that reduces the chances of misuse, making it a preferred choice among prescribers and users.
• Subutex is less controlled, which makes it a safer choice than Methadone 

There is more! read on as we discuss the following factors to help you make an informed decision. 

1. Ease of obtaining a prescription
2. Risk of Dependency
3. Use during pregnancy

No more waiting in lines with the ChoicePoint online medication prescription program! Our online Subutex doctors in NJ can dispense insurance-covered same-day prescriptions

Before comparing both medications, Let’s take a closer look at how both work.

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How Does Subutex Work?

Subutex (Buprenorphine) comes as an orange pill. It is a partial opioid antagonist, which means:

1. It binds to the same receptors as addictive opioids.
2. The binding is strong so that it can replace other opioids such as Fentanyl and Heroin.
3. Unlike addictive opioids that fully bind to the receptors and produce euphoria, it partially binds to stabilize the receptors in the absence of opioids.
4. This binding reduces withdrawal symptoms and cravings without creating a ‘high’

Methadone Working Mechanism

Methadone has levomethadone and dextromethadone as active ingredient. It is a full opioid antagonist that reduces cravings and withdrawal symptoms. It does not cause any euphoria because:

• It is gradually absorbed into the bloodstream.
• This slow onset prevents a rapid spike or rush associated with euphoria.
• Being a full antagonist, it can displace addictive opioids such as Heroin, Purple Heroin, Morphine, etc.

Disclaimer: This blog presents factual information but is not a substitute for medical advice. Please follow your doctor’s advice and prescription.

3 Key Factors To Consider When Choosing Methadone Vs. Subutex

Subutex offers more advantages that may make it the preferred choice for many individuals. Here are some factors that may be a deciding factor for you:

1. Risk of Dependency 

One of the deciding factors to consider when choosing between Methadone Vs. Subutex is their potential for dependency. Subutex is a safer option with manageable withdrawal symptoms and a lower risk of dependence and addiction.  

2. Convenience and Flexibility for Obtaining an Online Prescription

There are more strict prescription guidelines for Methadone than Subutex. Methadone is dispensed at Federally-licensed clinics only. Till COVID-19, users were not allowed to take home the prescription or dose. People had to wait in long lines to take their medicine at a Methadone clinic under the supervision of a doctor.

Now, take-home prescription guidelines are being relaxed, but clients can only take their dose at home if they meet specific criteria, and online methadone prescriptions are still not available. 

Subutex can be prescribed online, making it a more confidential and flexible option. It is a more practical option for working individuals as it eliminates the hassle of long commutes, waiting in lines, or visiting a rehab. 

Helpful Link: Where can I get a Subutex prescription?

3. Subutex Use During Pregnancy

Both medications are safe to use during pregnancy. However, research indicates that Subutex use during pregnancy has been associated with the following:

• Better neonatal outcomes
• Reduces neonatal abstinence syndrome 
• Reduced chances of preterm birth
• Improved baby birth weight

However, it should be noted that both medications offer greater benefits than no treatment. So, if you are an expecting mother, you should seek timely detox and withdrawal management to save your and your baby’s life. 

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The Battle of Methadone Vs. Subutex: The Final Verdict

Overall, both medications serve tremendous benefits. These reduce the chances of an opioid overdose, or relapse, and significantly improve the quality of life.

You can discuss medication that best fits your needs with your doctor. We have wrapped up the differences and similarities in the table below:

Online Subutex Prescription in New Jersey 

ChoicePoint offers hassle-free same-day Subutex prescriptions that you can get in the comfort of your home. Our Subutex doctors are accepting new patients in NJ, which means you can get:

1. Hassle-free prescription
2. Online MAT clinic
3. Comprehensive opioid treatment
4. Aftercare and relapse prevention plans
5. Insurance-covered treatment (BCBS subutex prescription, Medicaid, Medicare, and other insurance accepted)

ChoicePoint is a CARF-certified alcohol and drug rehab in NJ. We have helped hundreds of clients achieve lasting sobriety, and we can help you, too! Call 844.445.2565 to explore your treatment options.

Free Addiction Assessment

Please note this assessment is an initial self-screening, and it is not meant to be a medical assessment or clinical diagnosis of addiction. For proper diagnosis and treatment, schedule an appointment with ChoicePoint.

Frequently Asked Questions About Subutex Vs. Methadone

More of your questions related to Subutex Vs. Methadone is answered below:

Does Insurance Cover Subutex in NJ?

Most Medicaid and private insurance plans cover Buprenorphine-based treatments, including Subutex, but coverage varies. Some plans require prior authorization, and generic versions may be more affordable.

Why Choose Suboxone Over Methadone?

Suboxone (buprenorphine/naloxone) is often preferred over Methadone because it has a lower risk of dependency, overdose, and abuse. Suboxone is a partial agonist, meaning it provides relief from withdrawal without producing intense euphoria. 

Is Methadone Worse Than Subutex?

Methadone and Subutex serve the same purpose, treating opioid use disorder, but Methadone carries a higher risk of abuse, dependency, and overdose because it is a full opioid agonist. Subutex (Buprenorphine) is a partial agonist, meaning it has a ceiling effect, reducing the risk of overdose. 

Can You Take Subutex and Methadone Together?

No, taking Subutex and Methadone together is not recommended. Subutex contains buprenorphine, which has a high binding affinity for opioid receptors. If taken while Methadone is still in your system, Buprenorphine can displace Methadone from the receptors, triggering precipitated withdrawal.

Sources

1. Whelan, P. J., & Remski, K. (2012). Buprenorphine vs methadone treatment: A review of evidence in both developed and developing worlds. Journal of neurosciences in rural practice, 3(1), 45–50.
   https://doi.org/10.4103/0976-3147.91934
2. McCarty, D., Bougatsos, C., Chan, B., Hoffman, K. A., Priest, K. C., Grusing, S., & Chou, R. (2021). Office-Based Methadone Treatment for Opioid Use Disorder and Pharmacy Dispensing: A Scoping Review. The American journal of psychiatry, 178(9), 804–817.
   https://doi.org/10.1176/appi.ajp.2021.20101548
3. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Buprenorphine. 2023 Aug. Available from:
   https://www.ncbi.nlm.nih.gov/books/NBK582609/
4. Drug Enforcement Administration. ​ (2022, May). ​ Buprenorphine. Diversion Control Division, Drug & Chemical Evaluation Section. ​