Vyvanse stays in your system for about 5 hours but can be detected through a hair follicle test even after 3 months of the last use due to one of its metabolites, d-amphetamine. But how long does Vyvanse stay in your system depends on:
- Your age
- Your metabolism
- The amount of Vyvanse consumed
- The duration for which Vyvanse was taken
- Your health status
It is important to know how long does Vyvanse stay in your system because Vyvanse is a Schedule II controlled substance. It comes with a black box warning from the FDA (Food and Drug Administration) indicating that it has a high potential for abuse and dependence. Since it increases attention spans, people may use it recreationally to boost their academic performance or lose weight. The CDC (Centers for Disease Control and Prevention) reports that more than 4 million people have abused prescription stimulants, including Vyvanse, in 2022. That’s why Vyanase is not prescribed for more than two to three weeks of use.
ChoicePoint offers an insurance-covered dual diagnosis program to treat substance abuse and mental health illness. Contact us today to start your holistic care for ADHD and Vyvanse abuse 844.445.2565.
Table of Contents
What Is Vyvanse Prescribed For?
Vynase (generic name: lisdexamfetamine) is a prescription medicine for treating ADHD and eating disorders in adults and children older than 6 years. It stimulates your brain to:
- Improve Concentration
- Increase Attention
- Reduce Hyperactivity
- Bring Mindfulness
- Allows you to focus more
Vyvanse achieves this by increasing the levels of two brain chemicals- norepinephrine and dopamine. People with ADHD have low levels of these two chemicals. By increasing their availability, Vyvanse influences emotions, behavior, and thoughts to bring improvement in ADHD symptoms.

Did you know? Vyvanse works best around 70 mg, taken only once a day. But, usually, the starting dosage for both pediatrics and adults is 30 mg, which is then slowly increased to 70 mg over a few weeks.

Did you know? Vyvanse works best around 70 mg, taken only once a day. But, usually, the starting dosage for both pediatrics and adults is 30 mg, which is then slowly increased to 70 mg over a few weeks.
How Long Does Vyvanse Stay In Your System?
Vyvanse acts quickly, reaching its peak within the first one to two hours, but its effects can last for about 13- 14 hours. Vyvanse (Lsdexamfetamine) lasts only five hours before it starts leaving your system. However, Vyvanse’s metabolism quickly breaks down Lsdexamfetamine into d-amphetamine, which makes some residues of Vyvanse stay in your system for more than 5 hours.
Vyvanse Half-Life
How long does the Vyvanse stay in your system depends on its half-life of Vyvanse. Half-life is the time it takes half of the Vyvanse to leave your system. Vyvanse half-life is less than an hour, and it can take 4-5 half-lives for Vyvanse to leave your system completely. However, d-amphetamine has a half-life of 10-12 hours, and as a result, Vyvanse is detectable even after 2-3 days in your system.
Please note this assessment is an initial self-screening, and it is not meant to be a medical assessment or clinical diagnosis of addiction. For proper diagnosis and treatment, schedule an appointment with ChoicePoint.
Factors Determining How Long Does Vyvanse Stay In Your System
Besides the half-life of Vyvanse, there are a few other factors that will determine the time it takes for Vyvanse to leave your body. Here are these determinants:
Factors Determining the Vyvanse Duration | How Long Does Vyvanse Last? |
---|---|
Age and metabolism | Older people might have a slower metabolism, and it takes longer for their body to get rid of Lisdexamfetamine and d-amphetamine. |
Amount of Vyvanse taken | Taking larger doses of Vyvanse will allow you to eliminate it quicker. |
The duration of taking Vyvanse | Abusing Vyvanse for a long time can make it stay for longer. |
Kidney issues | A damaged kidney will take longer to excrete Vyvanse and its residues. |