How Long Does Fluconazole Stay In Your System?

Fluconazole (Diflucan) stays in your system for 5 to 6 days since your last dose. Fluconazole is a commonly prescribed antifungal medication and could also interact with other drugs, especially with alcohol. Therefore, if you or your loved one is a habitual alcohol user or abusing alcohol along with the usage of fluconazole. You need to learn about how long does fluconazole stay in your system,

• How long can Fluconazole be detected in various body parts?
• Fluconazole interaction with other drugs and Alcohol
• Fluconazole addiction

Did you know Fluconazole can be identified in routine drug testing, such as urine, hair, saliva, and blood tests? Call ChoicePoint a top-rated drug and alcohol rehab in NJ and request our at-home drug testing kit at your doorstep today! 

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What is Fluconazole?

Fluconazole is the generic version of the brand-name product Diflucan. It can be taken orally as well as an injectable antifungal medication. Fluconazole belongs to the azole antifungal class, inhibiting the growth of fungi by disrupting their cell membranes. It is typically administered either as a single dose for some infections or over a longer period for more persistent conditions.

Fluconazole is used to treat: 

1. Vaginal yeast infections
2. Urinary tract infections
3. Thrush in the mouth or esophagus
4. Blood infections 
5. Liver and spleen infections 

Understanding Fluconazole‘s Half-Life

Fluconazole’s half-life is 20 to 50 hours. It takes that long for half of the drug to leave the system. After a single dose, it stays in the body for about 5 to 10 days before being fully eliminated. The exact time can vary based on individual factors, but generally, it takes around 6 days for fluconazole to completely clear out of the system.

How Long Does Fluconazole Stay In Different Parts Of The Body

Fluconazole distributes well into various tissues and fluids. It helps in treating infections in different body parts. Here is a rough estimate of how long does fluconazole stay in different parts of the body:

a. Fluconazole in Bloodstream

Fluconazole can be detected in the blood for about 5 to 10 days.

b. Skin and Nails 

Fluconazole penetrates well and can stay in the skin for up to 7 days after a dose. For nails, where circulation is slower, it can take longer to reach effective levels. Therefore, it may linger for a more extended period after stopping.

c. Vaginal Tissue

Fluconazole usually remains effective for up to 72 hours. However, its antifungal effect can last beyond this time as it slowly clears from the body.

d. Urine

Most fluconazole leaves the body through urine, with 80% unchanged and 11% as processed by-products. Fluconazole can be detected in urine for up to 5 to 10 days after a single dose. 

NOTE: The body may need up to 6 to 7 days to eliminate fluconazole after the last dose that you took fully. These days, individuals may still feel the effects of fluconazole if they stop taking it. However, the drug’s effects normally stop after the end of the treatment, or very shortly after.

If you recently took Fluconazole and are feeling withdrawal symptoms, call ChoicePoint’s DEA-certified practitioner now at 844.445.2565! They will evaluate your symptoms and suggest the appropriate course of treatment immediately!  

Factors that Affect How Long Does Fluconazole Stay in the System?

As mentioned above, a drug’s half-life is how long it takes for half of it to leave your body. Fluconazole’s half-life is about 30 hours, so it takes around 6 days to fully clear after you stop taking it, but it keeps working during that time. A few factors may affect how long it stays in your system: 

• Intake of Fluconazole- A higher dose may cause the body to retain it for an extended amount of time. A single 150 mg dose may clear faster rather than a prolonged treatment regimen.
• Kidney Function– Fluconazole elimination may be delayed in those with certain kidney functions.
• Liver Function– Issues with the liver may potentially impact the metabolism and excretion of drugs.
• Age– With age, the body’s capacity to metabolize drugs may alter.  
• Metabolism- Individuals with good metabolic rates will process and eliminate fluconazole quicker than people with a slow metabolic rate.

Mixing Alcohol & Fluconazole (Diflucan)

Fluconazole Side Effects

No medication should ever be taken without the consultation of a healthcare provider. Fluconazole’s common side effects include:

• Headache
• Diarrhea
• Nausea or upset stomach
• Dizziness
• Stomach pain
• Mild constipation
• Vomiting
• Severe rash in people with bad immunity

Fluconazole Medication Interactions

Fluconazole is usually a harmless medication. However, it may interact with various drugs, potentially altering their effectiveness or increasing the risk of side effects. Here’s a detailed look at some common drug interactions with Fluconazole:

NOTE: Understanding Fluconazole interactions with different substances will help you use Fluconazole safely and effectively while minimizing potential risks. Always inform your doctor or pharmacist about all your medications and supplements to avoid harmful interactions.

When To  Contact Your Healthcare Provider About a Fluconazole Interaction?

You should contact your healthcare provider immediately if you experience any of the following after taking fluconazole. Especially if you mixed Fluconazole with any other substance:

1. Rash
2. Itching, or swelling (especially on the face or tongue)
3. Severe dizziness 
4. Trouble breathing
5. Yellowing of the skin or eyes (jaundice)
6. Persistent nausea or vomiting
7. Abdominal pain
8. Irregular heartbeat or palpitations
9. Difficulty staying awake 
10. Seizures

This list isn’t complete. Contact ChoicePoint if you notice any new or worsening symptoms after taking fluconazole. This is especially important if you mix Fluconazole with other substances.

Free Addiction Assessment

Please note this assessment is an initial self-screening, and it is not meant to be a medical assessment or clinical diagnosis of addiction. For proper diagnosis and treatment, schedule an appointment with ChoicePoint.

Importance of A MAT Program After Mixing Fluconazole with Other Drugs or Alcohol

Even after the last dose, Fluconazole can interact with other medications in your system. If you or someone you know mixed Fluconazole with drugs or alcohol, professional intervention is required immediately. A rehab can provide the support you need to recover. Here is how an addiction rehab program can help you if you mix Fluconazole with alcohol. 

1. Reduces Withdrawal Symptoms

MAT uses medications to alleviate withdrawal symptoms from substances, making the detox process more manageable and comfortable. 

2. Helps Manage Cravings

A MAT program can help reduce cravings for substances. Moreover, it can also help in decreasing the likelihood of relapse and aiding in long-term recovery.

3. Supports Recovery with Behavioral Therapy

MAT programs often include counseling and behavioral therapy like CBT and DBT alongside medication. They address the psychological aspects of addiction and help to develop healthy coping strategies. 

4. Addresses Co-occurring Disorders

MAT can help manage co-occurring mental health disorders, such as depression or anxiety, which are often present alongside addiction. 

5. Relapse Prevention and Aftercare Planning

A MAT program will work on developing strategies to avoid relapse. Including learning about triggers and how to handle cravings. Moreover, an aftercare plan will help you continue therapy, support groups, and lifestyle changes to support long-term recovery.

If you are looking for a drug and alcohol rehab in NJ that offers a rapid detox program for abuse of prescription medication, get in touch with ChoicePoint! We are officially in-network with BCBS of NJ, Optum in NJ, UnitedHealthcare, and other commercial insurance plans also including Medicare and Medicaid. 

Q/A Section For How Long Does Fluconazole Stay In Your System?

Here are some questions and their answers to help you understand How Long Does Fluconazole Stay In Your System.

1. Who Should Not Take Fluconazole?

Fluconazole should be avoided by those with: 

1. severe liver or kidney disease
2. known allergies to the drug
3. pregnant women(especially in the first trimester)
4. heart rhythm issues

2. Should You Take Fluconazole With Food?

Fluconazole can be taken with or without food. However, it is advised to take it with food because, during a clinical trial, a single dose of fluconazole caused nausea in as many as 7% of participants. When taking fluconazole with food, nausea may be lessened or avoided.

3. What Can You Do if You Experience Side Effects From Fluconazole?

If you experience side effects from fluconazole, contact your healthcare provider immediately. Follow their advice on managing symptoms, which may include adjusting the dose or switching medications.

4. Can You Take Viagra With Fluconazole?

Fluconazole can increase Viagra levels in the blood, potentially leading to more intense side effects like headaches, dizziness, or low blood pressure. It’s best to consult your healthcare provider before combining these medications.

5. Can Fluconazole Affect You After It Leaves Your System?

No! Fluconazole typically does not affect you after it has left your system. However, if you experience any side effects after the medication has left your system, do not delay consulting a healthcare provider for further evaluation.

References

1. https://www.ncbi.nlm.nih.gov/books/NBK537158/#:~:text=Elimination%3A%20Fluconazoletes. 
2. https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.891336/full 
3. https://www.accessdata.fda.gov/spl/data/c5396be9-5e15-4df3-85a3-adce93b92d8b/c5396be9-5e15-4df3-85a3-adce93b92d8b.xml#Section_7 
4. https://pubchem.ncbi.nlm.nih.gov/compound/Fluconazole