Can I take Fluconazole with Suboxone?

The straightforward answer to the question ‘Can I take fluconazole with Suboxone?’ is no. Suboxone treatment is a common medication used to treat opioid dependence. Conversely, fluconazole is an antifungal medication used to treat yeast and fungal infections. Despite their unrelated purposes, as they break down in the body, they exacerbate each other’s detrimental effects. As fluconazole impacts liver function, it results in fluctuations in the levels of Suboxone in the body. The main side effects of mixing these two can be drowsiness, lightheadedness, and breathing issues.

If you are taking fluconazole already and your opioid dependence requires you to take Suboxone, call 844.445.2565 our DEA-certified care providers before starting!

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How Fluconazole and Suboxone Are Metabolized 

To fully understand the answer to Can I take fluconazole with Suboxone, you need to know how these substances are metabolized in the body

3 Major Symptoms to Watch For When You Combine Fluconazole and Suboxone 

Here are the symptoms of using both medications:

1. Drowsiness, as it depresses the central nervous system
2. Dizziness due to slow brain functioning 
3. Respiratory distress due to the decline in oxygen levels²

Medical Advice and 4 Common Safety Tips While Combining Fluconazole and Suboxone

If you are seeking, can I take fluconazole with Suboxone? Use these tips for safety:

1. You may need a dose adjustment from primary care doctors who prescribe Suboxone or more frequent monitoring by your doctor to use any medication safely with Suboxone. 
2. Don’t combine fluconazole and alcohol, fluconazole and Tylenol, and other vitamins (vitamin A), supplements, and herbs that may cause an unwanted reaction.³
3. If you use other medications, vitamins, supplements, and herbs, fill out a medication list with the assistance of your doctor to prevent any inconvenience.
4. It’s also important to read the labels and other paperwork present in the box that may come with both medications. If you don’t understand the suboxone dosage guide, look for suboxone clinics around me.

Buprenorphine and Fluconazole Interactions

How to Prevent Fluconazole and Suboxone Interaction At ChoicePoint

If you want to take another medication with it, it is important to know how long does fluconazole stay in your system. Generally, it remains in the system for five to ten days. If so much information is leading to confusion, you can get help from ChoicePoint by:

1. Starting New Medication After Talking to Our Suboxone Doctors 

You can freely disclose all medications you are taking before starting any new medications. Our doctors listen to you navigate these kinds of details, making you feel better and less confused. If you are consuming fluconazole and alcohol in combination, that too with Suboxone, our addiction specialist offers guidance and support to avoid dangerous outcomes.

2. Getting Prescription, Dosage Recommendation, & Treatment Plans

Our online suboxone doctors that accept Medicaid are familiar with alternative medications and their safe dosages, which we can prescribe if needed. Additionally, it is prevalent in people with substance use disorder to have mental health disorders like anxiety and depression. We help you find the right mental health therapy to help your co-occurring disorders while minimizing negative interactions.  

Talk to a Suboxone doctor before starting any new medication to avoid any usual symptoms or complications. Call ChoicePoint at 844.445.2565 or book an appointment online. 

Common Questions Related to Fluconazole & Suboxone Intake

Here are some more queries that come under the umbrella of Can I take fluconazole with Suboxone.

What other drugs should not be taken with fluconazole?

Some of the medications that interact with fluconazole include Warfarin (Coumadin, Jantoven), amiodarone (Pacerone), and clopidogrel (Plavix). 

What other medicines should not be taken with Suboxone?

The medications you shouldn’t take with benzodiazepines, alcohol, and other opioids, antibiotics, antifungals, and antidepressants.

Can a pharmacist give you a second dose of fluconazole without having to go back to the GP?

For a second dose of fluconazole, you need to consult a general practitioner. 

How long does fluconazole take to work?

If you have a mild infection, 150mg of fluconazole starts working in one to three days, and you will start noticing improvement in the condition (fungal and yeast infections). 

Is a reaction after taking fluconazole normal?

Itching, skin rash, or fluconazole allergy is a very common symptom people report after taking it. Learn how long fluconazole side effects last and take notice of other symptoms like breathing issues, swelling of the face and throat, and hives. If symptoms persist for an extended period and are accompanied by other concerning symptoms, consult a doctor.

References 

1. CYP3A4 cytochrome P450 family 3 subfamily A member 4 [Homo sapiens (human)] – Gene – NCBI
   https://www.ncbi.nlm.nih.gov/gene/1576
2. HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].
   https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020733s031s032lbl.pdf
3. Fluconazole Tablets USP [Internet]. Fda.gov. https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/8f90f169-6a72-4c33-a2af-0bc943602bc2/spl-doc